Upinder Bhalla

National Centre for Biological Sciences
Session: standardization in multiscale modeling – connecting the levels

 

From neural recordings to subcellular neuronal computation.
Neural circuit activity is as much an outcome of subcellular and molecular computation as it is of spike integration. We are interested in three closely coupled problems: How to simulate multiscale neuronal models that span molecular, electrical, and structural events, how to define such models, and how to systematically parameterize them.
Emerging experimental techniques have thrown open the floodgates of data that may be used to parameterize and interpret models that cross scales. I will describe our efforts to harness these developments and learn from such models.